advisers reject Arena diet drug
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Arena shares fell nearly 40 percent canada goose outlet reviews in after hours trading Thursday to $2.28. The shares had been halted in regular trading pending canada goose outlet orlando results of the advisory meeting. Food and Drug Administration issued documents raising safety concerns that included the rat tumors and memory loss.
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do think (lorcaserin) is promising, but there too much uncertainty canada goose outlet vip at this time, said Jessica Henderson, the panel consumer representative.
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uk canada goose outlet The probability of lorcaserin ever reaching the market is small, BMO Capital Markets analyst Jason Zhang said after the panel vote. uk canada goose outlet
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cheap canada goose uk just couldn get over that we didn have a broader population that was representative of people most likely to get this (drug), said Dr. Lamont Weide, an advisory panel member and chief of diabetes and endocrinology at the University of Missouri canada goose outlet ottawa in Kansas canada goose outlet online reviews City. cheap canada goose uk
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Canada Goose Parka Drugmakers have failed for decades to produce a pill to help canada goose outlet jackets people shed a significant amount of weight without serious side effects. advisers agreed tougher action was needed on Abbott Laboratories Inc diet drug Meridia, but split on whether it should be banned. Canada Goose Parka
BLOCKING APPETITE Arena lorcaserin was designed to block appetite signals in the brain in a similar way to the now withdrawn fenfluramine in the fen phen diet drug cocktail. The Arena drug is more selective in the receptors it affects and the company says studies have not found any of the heart valve problems with lorcaserin that were linked to fenfluramine.
Arena also argued the findings of rat tumors did not apply to people because they resulted from high doses or biological mechanisms specific only to rodents. No increase in cancer cases was seen in people.
canada goose clearance sale Patients who took 10 milligrams of lorcaserin twice daily for a year lost about 5.8 percent of their body weight on average, FDA reviewers said. Placebo patients lost 2.5 percent canada goose clearance sale.